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The best indicator for Lilly (Eli) (LLY)

We backtested 20 indicators across daily, weekly and hourly charts on real Lilly (Eli) (LLY) history. Here's what actually worked — risk-adjusted, out-of-sample, with costs.

Oscillator · Daily

WaveTrend (8/6/4)

On the daily chart, this is the strongest risk-adjusted edge we found for Lilly (Eli) (LLY) over ~54.0 years — trailing buy-and-hold by 4.7% CAGR.

9.5%
CAGR
0.56
Sharpe
-56.8%
Max DD
73.8%
Win rate
2.26
Profit factor
-4.7%
vs Buy&Hold
Best by timeframe

The winner on each chart

Daily
WaveTrend (8/6/4)
-4.7% · Sharpe 0.56
Weekly
EMA 20/50 Cross
-4.5% · Sharpe 0.52
Full results

Every indicator, ranked

Ranked by Sharpe (risk-adjusted return). Hypothetical, fees included.

#IndicatorTFCAGRSharpeMax DDWinTradesvs B&H
1WaveTrend (8/6/4) Daily9.5%0.56-56.8%73.8%214-4.7%
2CCI Daily8.1%0.53-52.9%70.9%261-6.1%
3EMA 20/50 Cross Weekly9.6%0.52-60.9%50.0%28-4.5%
4Williams %R Daily7.5%0.5-64.2%70.6%354-6.7%
5EMA 50/200 Cross Daily8.0%0.46-71.1%26.2%42-6.1%
6Money Flow Index Daily6.7%0.46-52.4%81.7%60-7.4%
7SMA 50/200 Cross Daily7.4%0.44-67.9%47.6%42-6.8%
8Stochastic Daily6.2%0.44-60.2%68.1%279-7.9%
9Bollinger Mean-Reversion Weekly4.8%0.43-34.1%81.8%44-9.2%
10Williams %R Weekly5.8%0.43-44.1%82.4%74-8.2%
11Bollinger Mean-Reversion Daily5.3%0.42-53.6%70.5%227-8.8%
12Holy Grail Confluence Daily5.5%0.42-32.4%73.2%82-8.6%
13Donchian Breakout Weekly6.4%0.42-68.2%39.1%46-7.7%
14ADX / DMI Weekly5.6%0.41-64.5%45.9%61-8.5%

= held up out-of-sample. Hypothetical, costs included. See methodology.

What this means

For Lilly (Eli) (LLY), WaveTrend (8/6/4) on the daily timeframe gave the best balance of return and risk in our test. It still trailed buy-and-hold on raw return — but remember: this is a hypothetical backtest of a standard rule, not a recommendation. Markets change. See the methodology and disclaimer.

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