The best indicator for McKesson Corporation (MCK)
We backtested 20 indicators across daily, weekly and hourly charts on real McKesson Corporation (MCK) history. Here's what actually worked — risk-adjusted, out-of-sample, with costs.
ADX / DMI
On the weekly chart, this is the strongest risk-adjusted edge we found for McKesson Corporation (MCK) over ~31.7 years — trailing buy-and-hold by 2.8% CAGR.
The winner on each chart
Every indicator, ranked
Ranked by Sharpe (risk-adjusted return). Hypothetical, fees included.
| # | Indicator | TF | CAGR | Sharpe | Max DD | Win | Trades | vs B&H |
|---|---|---|---|---|---|---|---|---|
| 1 | ADX / DMI ✓ | Weekly | 11.1% | 0.67 | -39.5% | 59.0% | 39 | -2.8% |
| 2 | RSI Trend (>50) ✓ | Weekly | 11.1% | 0.6 | -51.5% | 43.4% | 76 | -2.8% |
| 3 | EMA 50/200 Cross ✓ | Daily | 11.1% | 0.58 | -52.3% | 50.0% | 18 | -2.9% |
| 4 | SMA 50/200 Cross ✓ | Daily | 10.6% | 0.57 | -53.0% | 54.5% | 22 | -3.4% |
| 5 | Donchian Breakout ✓ | Daily | 8.5% | 0.54 | -52.5% | 47.3% | 131 | -5.5% |
| 6 | EMA 20/50 Cross ✓ | Daily | 8.9% | 0.51 | -70.9% | 45.3% | 64 | -5.1% |
| 7 | Donchian Breakout ✓ | Weekly | 7.7% | 0.49 | -49.5% | 58.6% | 29 | -6.2% |
| 8 | Donchian Midline ✓ | Weekly | 8.7% | 0.49 | -65.8% | 47.2% | 72 | -5.2% |
| 9 | EMA-10 Trend ✓ | Weekly | 8.1% | 0.47 | -71.4% | 38.0% | 142 | -5.8% |
| 10 | Bollinger Breakout ✓ | Weekly | 5.8% | 0.43 | -53.4% | 54.1% | 37 | -8.1% |
| 11 | Bollinger Mean-Reversion ✓ | Weekly | 5.6% | 0.42 | -37.9% | 84.0% | 25 | -8.3% |
| 12 | EMA 20/50 Cross ✓ | Weekly | 12.6% | 0.62 | -50.4% | 40.0% | 10 | -1.3% |
| 13 | ADX / DMI | Daily | 4.9% | 0.38 | -44.7% | 39.5% | 200 | -9.1% |
| 14 | Stochastic ✓ | Daily | 5.5% | 0.37 | -50.3% | 70.5% | 146 | -8.5% |
✓ = held up out-of-sample. Hypothetical, costs included. See methodology.
For McKesson Corporation (MCK), ADX / DMI on the weekly timeframe gave the best balance of return and risk in our test. It still trailed buy-and-hold on raw return — but remember: this is a hypothetical backtest of a standard rule, not a recommendation. Markets change. See the methodology and disclaimer.
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