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The best indicator for Moderna (MRNA)

We backtested 20 indicators across daily, weekly and hourly charts on real Moderna (MRNA) history. Here's what actually worked — risk-adjusted, out-of-sample, with costs.

Trend · Daily

EMA 20/50 Cross

On the daily chart, this is the strongest risk-adjusted edge we found for Moderna (MRNA) over ~7.5 years — beating buy-and-hold by 30.1% CAGR.

43.4%
CAGR
0.93
Sharpe
-54.1%
Max DD
61.5%
Win rate
7.15
Profit factor
+30.1%
vs Buy&Hold
Best by timeframe

The winner on each chart

Daily
EMA 20/50 Cross
+30.1% · Sharpe 0.93
Weekly
Rate of Change
+23.2% · Sharpe 0.8
Full results

Every indicator, ranked

Ranked by Sharpe (risk-adjusted return). Hypothetical, fees included.

#IndicatorTFCAGRSharpeMax DDWinTradesvs B&H
1EMA 20/50 Cross Daily43.4%0.93-54.1%61.5%1330.1%
2Rate of Change Weekly36.4%0.8-63.9%45.0%2023.2%
3EMA-10 Trend Weekly30.3%0.73-52.1%44.4%2717.1%
4RSI Trend (>50) Daily23.9%0.67-75.6%38.0%9210.5%
5Donchian Breakout Daily22.6%0.66-61.2%41.7%249.2%
6RSI Trend (>50) Weekly23.1%0.63-78.0%40.0%159.9%
7ADX / DMI Daily20.2%0.62-53.1%45.8%486.9%
8EMA-10 TrendDaily19.2%0.59-88.9%38.0%1715.9%
9Donchian Midline Weekly21.6%0.61-55.4%50.0%148.4%
10Rate of ChangeDaily16.2%0.54-82.2%44.3%1152.8%
11Heikin-Ashi TrendWeekly14.6%0.51-77.4%38.5%651.4%
12Heikin-Ashi Trend Daily13.7%0.5-83.3%45.6%3550.4%
13Donchian MidlineDaily13.6%0.5-86.8%36.0%1000.2%
14Bollinger Breakout Daily9.8%0.43-67.1%39.4%33-3.6%

= held up out-of-sample. Hypothetical, costs included. See methodology.

What this means

For Moderna (MRNA), EMA 20/50 Cross on the daily timeframe gave the best balance of return and risk in our test. It beat buy-and-hold — but remember: this is a hypothetical backtest of a standard rule, not a recommendation. Markets change. See the methodology and disclaimer.

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